About 1 result found for searched term "PROTAC Bcl2 degrader-1 " (0.127 seconds)
| Cat.No. | Name | Target |
|---|---|---|
| M29577 | PROTAC Bcl2 degrader-1 | PROTAC |
| PROTAC Bcl2 degrader-1 (Compound C5) is a PROTAC based on Cereblon ligand, which potently and selectively induces the degradation of Bcl-2 (IC50, 4.94 μM; DC50, 3.0 μM) and Mcl-1 (IC50, 11.81 μM) by introducing the E3 ligase cereblon (CRBN)-binding ligand pomalidomide to Mcl-1/Bcl-2 dual inhibitor Nap-1. | ||
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